Familiestudier viser en ophobning af selvmordshandlinger i bestemte familie. Formålet med dette studie var at udføre en GWAS-analyser og beregne SNP-arvelighed for selvmordsforsøg i et landsdækkende udsnit af personer med og uden psykiatrisk sygdom. Dette var det største studiepopulation til dato og signifikante SNP-associationer til selvmordsforsøg blev fundet. Resultaterne viste desuden at genetisk transmission for selvmord ikke udelukkende kan forklares ved psykisk sygdom.
Studiet er publiceret i Molecular Psychiatry.
Studiet blev støttet at Lundbeck iPSYCH-bevillingen
DRISP: Annette Erlangsen & Merete Nordentoft
Samarbejdspartner:
- Vivek Appadurai, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Yunpeng Wang,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Gustavo Turecki, MD,
PhD , McGill Group for Suicide Studies, Douglas Hospital Research Centre, Department ofpsychiatry , McGill University, Montreal, Canada - Ole Mors,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Thomas Werge,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Preben B Mortensen, DrMedSc, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Anna Starnawska,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Anders D Børglum,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Andrew Schork, MS, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Ron Nudel, DPhil, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Marie Bækvad-Hansen,
PhD , The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark - Jonas Bybjerg-Grauholm, MSc, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- David M Hougaard, DrMedSc, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Wesley K Thompson, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
- Esben Agerbo, DrMedSc The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark