Suicide risk associated with psychiatric hospitalization

To examine the trend and excess risk of suicide in suicidal high-risk phases, namely among psychiatric inpatients and recently discharged patients. We will examine the risk in these high-risk phases according to sex, age-groups and psychiatric diagnoses.

DRISP: Trine Madsen, Merete Nordentoft & Annette Erlangsen

Suicide risk according to highest level of psychiatric service received

Different patient groups are seen across psychiatric sectors and it is relevant to know which groups are at imminent risk of suicide. In this project, the risk of suicide is examined according to the highest level of psychiatric service received. The level will be graded according to severity as well as by type of contact, such as psychiatric admission, psychiatric ER visit, psychiatric outpatient, psychiatric medicine.

DRISP: Trine Madsen, Merete Nordentoft, Annette Erlangsen

Lyme disease and risk of suicidal behaviour suicidal adfærd

We will examine the risk of suicidal behavior associated with Lyme disease. We will look into how this risk is according to age of infection with Lyme, number of infections, days hospitalized due to Lyme disease and time since Lyme disease.

DRISP: Trine Madsen, Merete Nordentoft & Annette Erlangsen


  • Michael Eriksen Benros, Research Unit, Mental Health Centre Copenhagen
  • Brian A. Fallon, MD, Center for Neuroinflammatory Disorders and Biobehavioral Medicine and director of the Lyme and Tick-Borne Diseases Research Center at Columbia University, USA

Combat exposure and risk of suicide attempt in previously deployed soldiers

In this study we have information on 13.000 deployed soldiers who reported on combat exposure after home-coming in a survey and this is linked to register-based data on self-harm/suicidal attempt.


Trajectories of suicidal ideations in different patient populations

In growth mixture modelling analyses we have examined the heterogeneity of trajectories of suicidal ideations. We have examined this in people with different diagnosis such as first episode psychosis, bipolar disorders and depression. Overall all these studies have found that between 10-20% of patients seem to have chronic suicidal ideations even after treatment has started.
The study has been published in Journal of Affective disorders.

DRISP: Trine Madsen


  • Andy Nierenberg, Harvard Medical School, Boston, Massachusetts
  • Ad Kerkhof, Vrije Universiteit, Amsterdam, Netherlands
  • Ole Mors, Aarhus University Hospital, Risskov, Psychosis Research Unit, Aarhus, Denmark
  • Ole Köhler-Forsberg, Department of Clinical Medicine, Aarhus University Hospital, Denmark

Traumatic brain injury (TBI) and risk of suicidal behaviour

We found that the risk of suicide is almost twice as high in people who experienced a TBI compared with people who had no TBI records. The risk was especially high in the first period after the TBI incident and oncreased by number of experienced TBI’s.

Internationale media
Washington Post
ABC News
The Telegraph (britiskmedie)

The study has been published in JAMA.

DRISP: Trine Madsen, Merete Nordentoft & Annette Erlangsen


  • Michael Eriksen Benros Research Unit, Mental Health Centre Copenhagen

Suicide rates in Nordic prisons 1999-2016

International research has shown an increased suicide rate among people in prison.  However, studies have yet to address age structural differences. In this longitudinal the suicide rates among male prisoners is compared to the general population in three Nordic countries, Denmark, Iceland, and Norway,  while adjusting for age differences.

Findings from the study shows that men in prison have a 7-fold higher suicide rate compared to the background population in Denmark, Iceland, and Norway and when accounting for age differences. For females, a rate 18-fold higher suicide rate was found among those in prison when compared to the general population. Over the 17-year study period, the suicide rate of people in prison decreased from 129 per 100,000 in 1999 to 70 per 100,000 in 2016. This decline was steeper that the decline observed for the suicide rate in the general population in the Nordic countries.

Link to study

DRISP: Britt Morthorst, Charlotte Mühlmann, Trine Madsen, Merete Nordentoft
og Annette Erlangsen


  • Lars Mehlum, Professor, National Centre for Suicide Research and Prevention, Institute of Clinical Medicine Oslo, Norway
  • Aiguröur Pàlsson, MD, Unit of Forensic Psychiatry, Iceland
  • Högni Óskarsson, md, Humus inc., Iceland Yngve Hammerlin, MD, Correctional Service of Norway Staff Academy, Norway

Infections and suicide

Findings suggest that infections might be linked to the development of psychiatric disorders and suicidal behaviour. To estimate the association between hospitalization with infection and the risk of death by suicide. An increased risk of death by suicide was found among individuals hospitalized with infection in prospective and dose-response relationships. These findings indicate that infections may have a relevant role in the pathophysiological mechanisms of suicidal behaviour.
The study was published in JAMA Psychiatry.
The project has received support from the Lundbeck Foundation.

DRISP: Annette Erlangsen, Trine Madsen, og Merete Nordentoft


  • Michael E. Benros , PhD, Mental Health Centre Copenhagen, Capital Region of Denmark, Denmark
  • Holger J. Sørensen, MD,Mental Health Centre Copenhagen, Capital Region of Denmark, Denmark
  • William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
  • Teodor T. Postolache, MD, Mood and Anxiety Disorders Program, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore